Welcome to the INIA Mouse Resources Core
The Mouse Resources Core is charged with delivering new mouse models to INIAstress
researchers and to the research community in order to effectively address questions
about the role of genetics in stress, anxiety, and excessive alcohol consumption.
The specific aims of this Core are as follows:
- The maintenance and distribution of novel mutant lines of mice produced by the ENU-mutagenesis
program. The production and availability of novel mouse mutants that have abnormal
alcohol, stress, and/or anxiety phenotypes represent an exciting resource for multi-disciplinary
studies by our INIAstress investigators. This part of the Core will make these lines
of mice available to INIA and community-wide researchers.
- The maintenance and distribution of the expanded BXD recombinant inbred (RI).
This
INIA has greatly expanded the phenotypic “space”
(molecular, cellular, and behavioral) associated with unique mouse reference populations
and this aspect of the Core will make these mice readily available to INIA researchers.
This includes the 50 newly developed BXD RI lines that arose, in part, from the
previous INIA support.
- The Behavioral Phenotyping component of this Core will provide more comprehensive
phenotypic information about EtOH and stress related behaviors in unique genetic mouse models that have been identified by high throughput behavioral screening within the INIAstress Consortium as exhibiting “extreme” phenotypes for EtOH and/or stress/anxiety
responsiveness.
- Neurohistological Phenotyping
- The distribution of the Knockout mice from the KO core.
Go to the Available Mouse Lines
What's New
INIA Stress anticipating the launch of the INIA Stress Resource Center Website.
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